To publicly available transcriptomic data from clinical trial RV144. The advantage and the reason that miRNAs are expected to be better biomarkers than gene expression markers is that a single miRNA is capable of regulating many. Outperforms the traditional Lasso approach on both prognostic and predictiveīiomarker identification in various scenarios. In a comprehensive numerical evaluation, we show that PPLasso Remove the correlations between the biomarkers before applying the generalized Our method consists in transforming the design matrix to PPLasso also takes intoĪccount the correlations between biomarkers that can alter the biomarker We propose a novelĪpproach called PPLasso (Prognostic Predictive Lasso) integrating prognosticĪnd predictive effects into one statistical model. Genomic data where biomarkers are highly correlated. Simultaneously select prognostic and predictive biomarkers in high dimensional Genomic data in such an area is hardly studied. Researches were mainly focused on clinical characteristics, and the use of Used to identify patients with potential benefit from the treatment. A prognostic factor is defined as any parameter, evaluated at diagnosis (or surgery), which is associated with treatment outcome (disease-free interval. Prevention of the occurrence of the disease, and predictive biomarkers can be Prognostic biomarkers can be useful for the ![]() Download a PDF of the paper titled Identification of prognostic and predictive biomarkers in high-dimensional data with PPLasso, by Wencan Zhu and 2 other authors Download PDF Abstract: In clinical trials, identification of prognostic and predictive biomarkers isĮssential to precision medicine.
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![]() Premier post-production programĪdobe Premiere Pro is suitable for professionals as it has a large array of features that meets the needs of editors from different industries. System RequirementsĪdobe Premiere Pro 14.0 for Windows requires a Windows 10 operating system with 8GB of RAM, 2GB of GPU VRAM and an Intel 6th Gen CPU. It can detect three frame sizes: 1:1, 2:1 and 4:1 which are Stereoscopic over/under VR, Monoscopic VR, and Stereoscopic side-by-side VR respectively. It can also detect a VR video based on the file’s frame dimensions. The program can detect three VR properties automatically, namely: VR Projection, VR Layout, and VR Captured View. The solution to this is to convert your MP4 file to MOV, MPEG-2 or FLV.Īnother format supported by Adobe Premiere is Virtual Reality or VR. Although it is a format that is supported by Adobe Premiere, some MP4 codecs may not be recognized by the program. ![]() You will find that most cameras and smartphones export media in MP4 format. File FormatsĪdobe Premiere Pro supports various video and audio formats, allowing you to have the same post-production workflow as professional editors. It does this by moving the Out point and In point of two clips either forward or backward in a sequence. The Rolling Edit is suited for fine-tuning your edit points. The Ripple Edit tool trims one clip and ripples the clips that proceed it, effectively closing the gaps between two edit points. In the post-production process, you will be using the Ripple Edit and Rolling Edit tools the most. This means it will move all file formats as it is displayed on the list. You can also opt to use the Track Select Forward/Backward tool as it allows you to select all of your media forward or backward. You will be using the Selection tool the most as it enables you to perform basic selections and edits such as marking specific edit points, selecting multiple clips and trimming audio tracks. In addition, Adobe Premiere has an extensive set of editing tools to edit videos, images, and audio. The EDL is vital to editors that create long-form videos as it contains an ordered list of reel and timecode data. This is done on its built-in edit decision list or EDL. ![]() This is because it has a non-linear video editing interface that allows all users to easily change the order of the media or revoke previous decisions. EditingĪdobe Premiere Pro is used by both new and seasoned editors. With Adobe Premiere, you can trim, splice and enhance different file formats as well as complete common video editing tasks to deliver broadcast-quality, high-definition videos. It has been used by professionals to edit movies, television shows, and online videos, but its comprehensive set of editing tools enables all users to produce their own content. It can also be installed independently from Adobe CC to your Mac OS or Windows PC. Adobe Premiere Pro is a video editing software that is included in the Adobe Creative Cloud. ![]() Home insurance: This box is for home insurance or renter’s insurance. You can also use this box for other home-related expenses like storage rental fees, monthly pet fees, parking fees, or any costs that aren’t otherwise covered in this section of the budget maker. Have a yard full of pink plastic flamingos because you’ll never answer to a HOA? Leave the box blank. HOA Fees: If your neighborhood has a HOA, you need to make sure you account for your fees in the budget calculator. If you own your home and your property taxes are not included in your mortgage payment, divide those taxes by 12 and add it to your mortgage - the goal is to ensure that your property taxes are covered in your monthly budget. Enter the amount of your monthly mortgage payment in the mortgage box, or the amount of your monthly rent in the rent box of the budget calculator. Mortgage or Rent: Whether you own or rent, you’ll need to factor in your housing expenses. Others, like groceries and entertainment expenses, will be estimates. Some of these costs, like rent and car payments, will be specific numbers. Once you’ve figured out how much money you’re bringing in each month after taxes, you’ll need to figure out how much you need to spend on your monthly expenses. Step 2: How to determine and enter monthly expenses You can also use this section to add a second income if you’d like to create a joint budget. If you have additional income such as a side hustle, or you receive child support, alimony, or other supplemental income, add that monthly amount under Other Income. If the last 3 months were unusually high or low, add up all your deposits for the past year instead and divide by 12 to get a better average. ![]() Enter that amount in the budget calculator. If your income changes from month to month, add up your total monthly deposits for the last 3 months and divide that number by 3 to get a baseline monthly estimate.If you get paid every other week, multiply your take-home amount by 26 for the number of checks you get each year, and then divide by 12 to get your monthly take-home pay.If you get paid twice a month, add the take-home amount of your two checks together and enter that amount.If you get paid a regular check once a month, enter your net income after deductions each paycheck.To determine what to enter under Salary/Wages in the budget calculator, follow these steps: Remember, this is the amount you can spend every month, so be sure to use your net income - which is the money you’re left with after taxes and deductions for things like health insurance and your 401(k), not your gross income, which is your total pay before any deductions. Ready to get started? To use our monthly budget calculator, first you need to figure out your monthly income. Build your budget in 3 easy steps Step 1: How to figure out your monthly income ![]() The PSM cover also doubles as the cover for the exhale valve. A similar design (which is patented by Avon) can be found on Avons M50 and its variants. ![]() The Primary Speech Module works via reverberating the noise coming from the exhale valve port and the space around it to make the user more easily understood, this eliminates the need for a forward-facing speech diaphragm. Speech clarity in the S10 stems from 2 places, the Primary Speech Module or as Avon calls it the "speech cone" and the Secondary Speech Transmitter, better known for being the radio port. The rings themselves can be removed via the help of the S10 repair kit to allow for replacement of broken/damaged lenses however to do this without the correct tools is both difficult and could end up damaging/breaking the lens assembly. S10 Lenses are held on with plastic rings that have rubber gaskets, these outer rings/ridges also provide outsert capability. These specialized corrective lenses have several disadvantages when compared to the L2A1 lenses, namely the FOV is significantly reduced and (similar to the S6) it causes a "fisheye" effect when looking out the outer side. However, it prevents any use of the optical correction inserts which require a separate lens type which is referred to as "corrective lens" (respirator designation 元A1). The more common indented Lens which is known as a "plano lens" (respirator designation L2A1) allows for use with optics and provides minimal disruption to the field of view. The S10's basic layout consists of 2 round lenses, a forwards facing exhale valve with integrated Primary Speech Module and 2 ports on each lower side of the respirator which on regular S10's house the Secondary Speech Transmitter (And clansman radio system port) on one side with the filter port on the other.ĭiagram from Survive to Fight detailing components of the S10Įyepieces on the S10 consist of a rather brittle plastic and come in 2 different types. The mid-life redesign took place just after the Gulf war to correct and improve certain parts and features of the S10 respirator, which are harness buckle tabs, orinasal cup, valve rubber specification and lower harness buckle attachment point on the mask itself. This was due to the design of the S10 being centred around a hypothetical war in Europe between NATO and the Warsaw pact, however many of the issues presented were resolved in the coming years with minor amendments to the design but the issue with heat continued to plague the S10 up until it was phased out. After mass production had started issue began sometime in 1987 with its first major trial being in the gulf war where several issues in relation to hot environments arose: namely the harnesses slipping, poor ventilation and valves sticking. ![]() Information from these documents will be added once it can be researched.Ĭoming off a successful trial the S10 respirator entered production in 1986 with Avon Rubber plc as the only contractor for the mask (marking the first time a service respirator of Britain has only had a single manufacturer) this is despite a Soviet document alluding that LBR possibly had involvement in the development cycle however this is currently unconfirmed. Leading on from this several prototypes were developed in the early 1980s by Porton Down and possibly Avon Rubber along with Layland Birming Rubber with field trials having seemingly started in 1982 with the last known prototype dating from 1984. With the exception of the R8 none of these designs made it into production, and even with the R8 its issuing was extremely limited at best and by the early 1980s, the S6s age was becoming more and more apparent leading to the NGASR 3848 document being issued setting out a list of requirement and expectations that the respective branches desired from a new respirator. These experiments and tests culminated in the R# series of respirators (including the R8 often wrongly called the S8) these experiments revolved around better performance with optical equipment and furthering resistance to threats. As the S6 respirator was nearing the 20-year mark of service the evolving CBRN threats presented in the late cold war prompted Porton Down to begin research and development on a new service respirator. With our watch-style dive computers, you can. 41 mm … You want to reverse with confidence in larger vehicles or with trailers - even in the dark. GARMIN AUTOLAND AND … Garmin Support Center is where you will find answers to frequently asked questions and Connect Garmin Express Garmin Pay Garmin Pros Garmin Technology Shop All Sales Subscription & Service Plans Student Athletes Watch Finder Design Your Cars Motorcycles Trucks RV Motorsports Off-Road Dash & Backup Cameras. Written by Matthew Miller, Contributing Writer on Aug. When the cab of a truck is your workspace, you want the long-haul peace of mind that Garmin trucking products deliver.
![]() It’s just another piece of paper in your stack of stuff to do for the day, but that piece of paper might be the whole world to the Soldier at the time. To you, it’ll just be another action, promotion, leave form or whatever. Of course you’ll have crappy days, but what job doesn’t have those? One piece of advice that I’ll share with a future 42A – No matter what you’re working on, take care of the Soldiers and treat their paperwork as your own. You stay busy and learn a great deal about the Army. ![]() That goes from the joes on the line to the CSM (Command Sergeant Major). If you learn your job, news will travel fast and you will get the respect of guys in your unit. You network a lot being a 42A, whether it’s in your own battalion or around your brigade. In answer to a question from a future enlistee considering 42A, one 42A said this “You will be at your desk for majority of your time. Sergeant Isabel Giron, a 42A at the Joint Multinational Readiness Center, Hohenfels, Germany HR Specialists know more about assignments, advanced schools, and promotions than any other soldier, because that is their job, from battalion to the Human Resource Command at Fort Knox, Kentucky, where there are a gazillion HR Specialists determining all soldiers’ assignments. Every personnel action that affects a soldier is handled by a Human Resource Specialist, including awards, promotions, schools, and assignments. Promotions are in line with most support jobs, and they are the ultimate POG’s (Person Other than Grunt), but they do get a lot of satisfaction in performing their work, because their job is taking care of soldiers. If they are airborne they will probably jump once every three months, to keep up jump pay. If they deploy they rarely go outside the wire, because their job is behind a desk and a computer. If they go to the field whether they are in a tent or a mobile shelter, they are behind a desk and a computer. They qualify with their rifle, go through the gas chamber, and take a PT test once a year, and they do PT (Physical Training) every weekday morning just like every other soldier, but their working day is behind that desk and computer. If you can’t stand being inside all the time, this is not your job. If you want to do a lot of shooting, blowing up things, and kicking down doors, this is not your job. The top rated job in the Army, by people doing it was Human Resource Specialist, 42A’s gave their job a 4.3 out of five rating. In 2015, Glassdoor surveyed soldiers to have them rate their jobs. The big jobs website “Glassdoor” has workers rate companies on a scale of 1 to 10, and they have workers rate how they like their job on a scale of 1 to 5. ![]() It is a solid desk job, and is continually rated high by the people doing it. It is physically one of the easiest jobs in the Army. The most “in the know” job in the Army is Human Resource Specialist, MOS (Military Occupational Specialty) 42A in the Adjutant Generals Corps. Steering on this truck is a standard wheel, more like a car than an ATV, which can be easier for younger kids to get the hang of. ![]() This single-seater vehicle features a seat belt over the waist to keep fidgety riders in place, and has grab handles located all around for bracing. MCGRATH ENDORSED: Develop a champion with the Razor Dirt Quad inspired by the winningest supercross rider, Jeremy McGrath. It also means your kid can have the time of their lives without the danger and risk that comes from letting them drive themselves. Offer available on approved purchases of select new unregistered Kawasaki vehicles. SLA/AGM spill proof battery has a characteristic of high discharge rate, wide operating temperatures, long service life and deep discharge. Incentives are available at participating Kawasaki dealerships. That means you can take your kid for a ride while you sit back and relax. YTX14-BS is a 12-Volt 12 Ah 200 Cold Cranking Amps (CCA) Sealed Lead Acid (SLA) battery. To start, this Jeep-style truck can be operated manually by your child, or via the included remote control. Though the style of this vehicle is certainly a little different than the other ATVs on our list, we couldn’t resist adding it due to its long list of features. Includes off-road windshield, roll-bar, shoulder harness, bucket seats and cup holdersĢ4-volt rechargeable High Output battery and charger includedįree 2nd year Warranty extension with consumer participation.Best Choice is one of the most popular brands when it comes to anything kid-related, and their Ride-On Car Truck is no exception. Here at Big Toys Green Country we offer the largest selection of 24v Ride on Vehicles and ATVS for your kids Our 24v Ride on vehicles offer the most speed and power for your toddler ready to get the next best ride on. Includes 12 month battery replacement warranty. 24 inch seat height Cool colors and barbed-wire camo patterns SKU: CL-ATV-3125XR8-U-ARMYGREEN. Battery Pack with Harness for Razor® Dirt Quad Electric ATV Set of two 12 Volt 8Ah batteries with plug-and-play wiring harness and connector for the Razor® Dirt Quad electric all-terrain vehicle. Polaris Sportsman 850 ATV 24-Volt Battery-Powered Ride-On, Silver: Drives on grass, dirt and hard surfaces 2-Speeds: 3. Peg Perego Polaris RZR 900 12-Volt Battery-Powered Ride-On, Camo. Side-by-side seats for two passengers and extra leg room for larger children Razor Dirt Quad - 24V Electric 4-Wheeler ATV - Twist-Grip Variable-Speed Acceleration Control, Hand-Operated Disc Brake, 12' Knobby Air-Filled Tires. Showing 1 - 50 of 54 products in All Powersports Products ATVs, Quads and 4-Wheelers Refine. Peg Perego Polaris RZR 900 12-Volt Battery-Powered Ride-On, Camo. Super traction wheels with Red Line Nitirile traction bands designed to perform like real ATV tiresįM radio with electronic tuning and MP3 input (2 AA batteries required - not included) Our 4wheelers are powered by 24 Volt batteries making this a great first option as your kid transitions to larger power wheels, atvs and 4 wheelers. Includes variable speed accelerator and automatic brakes for control and longer riding time (increases riding time by up to 27%). Switches easily to reverse mode, just like the real deal. Ride On ACCESSORIES Specifications of Polaris Ranger 24V RZR Ride On ATV: 2-Speedsģ.5 to 7 mph on grass, dirt or hard surfaces (7 mph lockout for beginners). 1 Year Manufacturer's Warranty and can be extended for free by registering with the manufacturer. Side-by-side seating lets kids take their friends with them on their outdoor adventures for double the fun! Shoulder harnesses, cup holders and a windshield roll bar are the perfect built-in accessories to give the Peg Perego Polaris Ranger RZR Green Shadow the complete true-to-life look. ![]() Two AA batteries required for FM radio – not included. Keep the fun times going with the included 24-volt rechargeable High Output battery and charger. ![]() Large super traction wheels with Red Line Nitrite traction bands add to the realism of the children’s ATV. They’ll love the fun-factor and realism of individual bucket seats, SmartPedal variable speed accelerator, power brakes, working rear suspension and an FM radio with MP3 input. This 24-Volt Super-Power allows 5 to 10 year-olds to drive over most terrain at speeds of 3½ to 7 mph. Perfect for exploring and taking on the world, with the Polaris Ranger RZR fun and excitement is always there to be had. Your kids will love the outdoors as they create new adventures with their own Polaris Ranger RZR Ride On ATV. Download doubleTwist Sync for Windows 10 for Windows to sync your iTunes playlists, ratings, DRM-free video and more to your Android phone with doubleTwist Sync. DoubleTwist Sync is a new, lightweight app for your PC to sync your music, videos and pictures over USB or over WiFi. Download doubleTwist 3.0.6 APK - doubleTwist is a music player and podcast manager that features a beautiful interface and clear controls. Sync your iTunes playlists, ratings, DRM-free video and more to your Android phone with doubleTwist Sync. Transfer your iTunes music library from your Windows PC to your Android device with doubleTwist Sync. DoubleTwist Sync supports free iTunes sync over USB and there's an optional premium upgrade for wireless synchronization using AirSync. Download Apps/Games for PC/Laptop/Windows 7,8,10. 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Download The Mod Apk Latest Version of DoubleTwist Pro, The Best Music & Audio App of Android, This Pro Apk Is Provides Unlocked All Premium Features & No. doubleTwist is a media management app that organizes and syncs the iTunes playlists, videos and photos on your Android phone. Plus, you can cast or AirPlay music from your Android with the optional AirSync purchase!ĭoubleTwist Music Player has been recommended by the New York Times, BBC, Wall Street Journal and numerous tech publications. The doubleTwist Player for Android can find and sync all of the music, podcasts, and video on your phone. ![]() Unlike other music players, doubleTwist is a free download, not a "trial". We update it frequently and listen to your feedback to make it better. ![]() We make money from an optional in-app upgrade to doubleTwist Pro unlocking the following premium music player features: DOUBLETWIST APP DOWNLOAD UPDATE ♬ Removal of ads in the podcast & radio screens.ĭoubleTwist is handmade with ❤ in Austin, Texas, live music's world capital. Thanks to you, we manage music & podcasts for more than 10 million loyal listeners. ![]() In Old Maid and several games of the Hearts family, it serves as a single, powerful card in the deck. I know plenty of kinksters, not so much the raceplay folks TBH, and I have never heard of this or any variation other than Queen of Spades or whatever the hell the anklet symbol for "hotwife" was, which I no longer remember but is probably where the spade symbol came from.Įdit, postscript: Tells you more about the OP's friend than anything else.The queen of spades (Q ♠) is one of 52 playing cards in a standard deck: the queen of the suit of spades ( ♠). ![]() And I say that because there's just no goddamn way something as generic and ubiquitous as "Queen of Hearts" could be coopted into something so specific as "Asian women for white dick only." The rest of that is shit from people who are hot for raceplay trying to get traction for whatever their particular kink is. I suspect that like alot of shit on urban dictionary, et al, it's mostly made up or is desperately being flogged by a tiny population of people who want it to mean something but to the rest of the world it doesn't at all. Tl dr: Got a tattoo, turned out to symbolize love for extra large vanilla snow cones, didn't know about it, am now super embarrassed D: I'm beyond worried that others may think I'm some kind of deviant. Luckily it's in a place that's kind of easy to hide. I am super embarrassed by it whenever I go out in public. who happens to also have a white boyfriend who also didn't know anything about any of this as the tattoo was my idea completely. He even showed me the raceplay subreddit which was. As he showed me on some of the urban dictionary definitions and pulled up pictures of other asian or ethnic girls with the tattoo. Apparently it is pretty popular among gay Asian men and Asian swinger couples to show their love for hung white dudes. I happily showed him my new tattoo and he immediately remarked on it, "Wow, I didn't know you were into that stuff girl!"Ĭonfused, obviously, I asked him what in the hell he was talking about.Īnd it turns out my tattoo was related to apparently pretty popular raceplay involving white men dominating non-white women or men. unfortunately, the other day I was talking with one of my friends who happens to be of the gay, male, and Asian persuasion - while I am a straight Asian girl. But yeah, just a Queen of Heart tattoo on my body. Here it is a little bit after I first got it:Įdit: Pic removed due to harassment. He is supposed to be getting a King of Hearts tattoo soon. I got it because I met my boyfriend at a casino (I know, I know) and I am supposed to be the "Queen" of his heart and because we both love playing card games. It is supposed to stand for Queen of Hearts. The tattoo is a little heart with a Q above it. So! In a wild turn of events, the most recent tattoo that I got turns out to have a separate meaning than the one I intended. Related Subreddits /r/TIDTRT (Today I Did The Right Thing) /r/IdeasforTIFU (Feedback) /r/AnimalTIFUs (Animals Fucking Up) /r/pranks (Today I Pranked) /r/TIGFO (Today I Got Fucked Over) /r/TifuCircleJerk (Make fun of r/TIFU) Friends & TINetwork Notes TIFUpdate if you are posting a follow-up post to update us on your story, you can start it with "TIFUpdate".Īntivaxx rhetoric or participation on antivaxx subreddits is cause for a ban from this subreddit. This covers implying you will set up a stream/public link/onlyfans in the future, having set up one in the past, or anything along the lines of "upvote this comment if you want me to do this." These examples are by no means comprehensive, just don't self promote. Even if not mentioned within the text of the post, alluding to links on your profile is not allowed. No making posts with the express purpose of promoting your business/video game/porn career. No low-effort "this didn't happen" type comments. No personal attacks on other users, no name-calling. ![]() No racism/bigotry/homophobia/transphobia. No humblebrags or stories that have zero consequences and don't go anywhere. Getting robbed, scammed, attacked, cheated on, etc, is not TIFU 4. Not your grandma, not some dude you saw in the newspaper. (3) All posts must have a "TL DR summary" at the end. (2) All posts must have at least 750 characters in the body. Use proper formatting: (1) All titles must start with TIFU. Share your stories and laugh along with the internet. We all have those moments where we do something ridiculously stupid. A community for the dumbass in all of us. ![]() These were the road jerseys for the Clippers for the first decade. you know, aside from that whole “sleeve-phase” the NBA went through. The baby blue, red and white looks really clean, and it gives the Clippers a one-of-a-kind uniform in the NBA. I’ve always been a fan of this color scheme, and really hope that the team eventually transitions back to this. I’m an absolute sucker for the baby blue, and it just works so well for the Clippers. Nonetheless, sleeves aside, these are some of my favorite Clippers jerseys ever. If this didn’t have sleeves, it would be higher on my list, however the sleeves just ruin them for me. If you read my piece on the San Diego uniforms, you know that I was really torn about this jersey. This jersey stands fine on its own, but when you compare it to what came before it. I liked what they did on the side of the jersey with the red and blue, and the change of numbers looks really good here. The logo on the front was smaller, and I personally wasn’t a fan of the blue letters with a red outline. These were fine, and I actually like them a lot, but they were definitely a downgrade from their previous ones. The Clippers re-branded and made these their home uniforms for five years. ![]() Maybe the blue is too dark? Maybe it’s the white outline? I want to like them, but like I said, there’s just something about these that has them near the bottom of my list. It was the only jersey that said “Los Angeles” on it as opposed to “Clippers”. ![]() The Clippers didn’t wear these too frequently during the decade, and maybe there’s a reason why. I’m still trying to figure it out, but there’s just something about these uniforms I could never get behind. They have the logo near the top of the jersey, but it just seems way too low, pushing everything else on the jersey lower than they need to be. They switched from white numbers to blue numbers, and I just don’t think it works well here. It looks too small, and it just doesn’t really pop. They made the switch on the front, putting “Los Angeles” as opposed to just “Clippers”. Too many things were changed with this road jersey that I just didn’t like. As I’ll mention later in this article, the road jersey the Clippers wore prior to this one was simple, but yet it worked. The red looks great, and that’s about it. I appreciate what they were going for and love that these were supposed to look vintage and retro, but these were a miss. The font looks awful, the numbers are too big, and the stripes are all over the place. Thank goodness they wore em for only one season.īaby blue looks great, and the stars on the side are nice, but overall these look like they were created by an elementary school student. Stars (2012)Ĭelebrating the 45th anniversary of the ABA’s founding, the Clippers unveiled this red, white and blue jersey in 2012. We’ll be going over the best and the worst of the Clippers uniforms from 2000 through 2014. The team re-branded in 2000, and then they did the same a decade later. Today, we’ll be ranking some of your favorite Clippers jerseys, and likely the uniforms they wore when you became a fan of the team. We’ve highlighted the jerseys from Buffalo, San Diego and the early Los Angeles days. This is the fourth edition where we’ve been ranking Clippers uniforms throughout the history of the team. |
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